منابع مشابه
Imaginal discs
and clatter. The Italians call them buffone — clowns. The large white grubs feed on roots and can be a major pest of grass and potatoes. Now controlled by pesticides, they were once far more abundant locally. In 1574, adult cockchafers were so numerous in the Severn Valley that their drowned bodies blocked the wheels of watermills, the book describes. In parts of Europe, if not in Britain, the ...
متن کاملWingless degradation in Drosophila imaginal discs
Wingless is a secreted signalling molecule with multiple roles in patterning developing Drosophila. Previous work has shown that in the Drosophila embryonic epidermis, regulated degradation controls the distribution of Wingless protein, leading to an asymmetric range. The actual mechanism of Wingless degradation is not currently understood. I have used gain and loss of function experiments to e...
متن کاملPeripodial Cells Regulate Proliferation and Patterning of Drosophila Imaginal Discs
Cells employ a diverse array of signaling mechanisms to establish spatial patterns during development. Nowhere is this better understood than in Drosophila, where the limbs and eyes arise from discrete epithelial sacs called imaginal discs. Molecular-genetic analyses of pattern formation have generally treated discs as single epithelial sheets. Anatomically, however, discs comprise a columnar c...
متن کاملDissection and immunostaining of imaginal discs from Drosophila melanogaster.
A significant portion of post-embryonic development in the fruit fly, Drosophila melanogaster, takes place within a set of sac-like structures called imaginal discs. These discs give rise to a high percentage of adult structures that are found within the adult fly. Here we describe a protocol that has been optimized to recover these discs and prepare them for analysis with antibodies, transcrip...
متن کاملSignaling Reaches to New Dimensions in Drosophila Imaginal Discs
Finding that peripodial cells in wing and eye imaginal discs are essential for the growth and patterning of the separate layer of disc cells now opens the study of interacting cell layers to the powerful developmental genetic techniques with which the Drosophila system is blessed. We can anticipate that future work will identify how such interactions contribute to patterning and how the mechani...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2010
ISSN: 0960-9822
DOI: 10.1016/j.cub.2010.03.010